Missouri State Website Small Business Events in Your Area Doing business in the state 24/7 Missouri Business Online Business Registration Secretary of State - Businesses Department of Economic Development Taxation Department of Revenue - Business Tax Employer links Department of Labor and Industrial Relations Unemployment Insurance Tax New Hire Reporting General Small Business Administration - Missouri State Agencies, Departments, Boards and Commissions Division of Purchasing - Office of Administration Regulated Industries Missouri General Assembly SBA.gov's Business Licenses and Permits Search Tool allows you to get a listing of federal, state and local permits, licenses, and registrations you'll need to run a business. Related topics State government websites